PTSD Molecular Process

Standard

1) The stress of smelling a predator scent impairs neuropeptide Y release.
2) This reduction in neuropeptide Y release enhances short-term plasticity of TA synapses. 3) The enhanced plasticity, in turn, boosts the strength of that pathway to drive more spiking of CA1 nerve cells.
4) Increased spiking alters the hippocampal output, a changed output that may increase the consolidation of fear learning.

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