Gender Orientation Set at Birth

Standard

“Epigenetically programming gender identity
by Leslie K. Ferrarelli

The presence or absence of a Y chromosome dictates our biological gender.  However, the brain is wired to be female unless exposed to testicular steroids (such as androgen and its metabolite estradiol) during a sensitive period shortly before and after birth.   The most sexually dimorphic region in the brain is the preoptic area (POA)…steroid-induced gender identity in the POA is mediated by an epigenetic mechanism, specifically DNA methylation…methylation were lower in the POA of male newborn rats than in those of female newborn rats….The findings further define how neurological gender identity is determined.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s