“Narcissists tend to have weaker connections between two important brain regions involved in self-esteem: the ventral striatum, which is associated with reward, and the medial prefrontal cortex, which is associated with your sense of self. People with high self-esteem have stronger connectivity between these two areas; in people with low self-esteem, on the other hand, that connectivity tends to be weaker. And narcissists, as it turns out, experience a “neural disconnect” here.”

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